Relief in a dye-free, convenient 3 oz. roll-on! Targeted pain relief for muscle-related injuries, strained muscles, or painful joints. Biofreeze gel helps increase blood flow and warming of the affected region. It does not contain waxes, oils, aloe, or petroleum, but it does contain ilex, an herbal extract from a South American holly shrub. The inclusion of ilex helps it achieve full penetration of the cold therapy medication. Can be applied up to 4 times daily.